Niacinamide 500 mg

FAQ's for Niacin

• How come my skin goes red and blotchy?

  This is called Niacin Flush. Niacin flush is a common side effect of taking high doses of niacin (vitamin B3), especially in its immediate-release form.

• What is a Niacin Flush?

  A niacin flush is a temporary reddening and warming of the skin, usually on the face, neck, chest, and arms. It’s caused by vasodilation—the widening of blood vessels—triggered by niacin.

• What Causes It?

  When you take niacin, it stimulates the release of prostaglandins, which expand capillaries and increase blood flow near the skin’s surface. This causes:

  • Redness

  • Warmth or heat

  • Itching or tingling

  • Occasionally mild burning

  The effect typically begins 15–30 minutes after taking niacin and can last up to an hour.

• When Does It Happen?

  More likely with immediate-release niacin (e.g., supplements over 50–100 mg). Less common with slow-release or no-flush forms (like inositol hexanicotinate). The Flush may decrease over time as the body adapts.

• Is It Harmful?

  No, it’s usually harmless—just uncomfortable. However, very high doses of niacin (above 2000 mg/day) should only be taken under medical supervision due to potential liver toxicity.

• How to Reduce or Prevent a Niacin Flush?

  • Take niacin with food

  • Start with a low dose and increase gradually

  • Try sustained-release or no-flush formulations

  • Avoid alcohol or hot beverages when taking niacin

  • Some people use aspirin (81–325 mg) 30 minutes beforehand (consult a doctor first)